Ann Home is on Trương Định street in District 1, the central district of Ho Chi Minh City. Cafés and restaurants lie within 50 m, among them Trung Nguyên Legend Café, Saigon Cocktails and Nhà Hàng Ringer Hut, and the Sri Mariamman Temple, a Hindu temple, is also 50 m away. Tao Dan Park, a central green space, is 400 m away, and the Museum of Ho Chi Minh City lies 550 m off.
Ben Thanh Station, a metro station on Line 1, is 300 m away, a walk of about four minutes, and the Bến xe buýt Sài Gòn bus station is 900 m. Saigon Railway Station is 2.2 km away, and Tan Son Nhat International Airport is 5.3 km away, with an airport shuttle offered for that transfer. Travellers arriving by train or by bus will find these stations close to the hotel.
On foot, Independence Palace, the former presidential palace of South Vietnam, is 500 m away, a walk of about six minutes, and Ben Thanh Market, a covered market known for its food stalls and souvenirs, is 250 m. The War Remnants Museum, with its outdoor displays of military equipment, is 850 m away, and Nha Rong Wharf, on the Saigon River, is 1.3 km away.